Fundamentals of Clinical Trials PDF

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Download PRETITLE Fundamentals of Clinical Trials [Kindle Edition] POSTTITLE from 4shared, mediafire, hotfile, and mirror linkThis is the fourth edition of a very successful textbook on clinical trials methodology, written by three recognized experts who have long and extensive experience in all areas of clinical trials. Most chapters have been revised considerably from the third edition. A chapter on ethics has been added and topics such as noninferiority and adaptive designs now receive considerable discussion. There is much new material on adverse events, adherence, data monitoring, and issues in analysis.
This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials from a variety of medical disciplines to illustrate the fundamentals.
The text is organized sequentially from defining the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areas include pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organizational structure, estimating an adequate sample size, specifying the randomization procedure, implementing the intervention and visit schedules for participant evaluation, establishing an interim data and safety monitoring plan, detailing the final analysis plan, and reporting the trial results according to the pre-specified objectives.
Although a basic introductory statistics course is helpful in maximizing the benefit of this book, a researcher or practitioner with limited statistical background would still find most if not all the chapters understandable and helpful. While the technical material has been kept to a minimum, the statistician may still find the principles and fundamentals presented in this text useful. This book has been successfully used for teaching courses in clinical trial methodology.Direct download links available for PRETITLE Fundamentals of Clinical Trials [Kindle Edition] POSTTITLE

• Product Details
• Table of Contents
• Reviews

• File Size: 2026 KB
• Print Length: 400 pages
• Publisher: Springer; 4 edition (September 21, 2010)
• Sold by: Amazon Digital Services, Inc.
• Language: English
• ASIN: B008BA6JEC
• Text-to-Speech: Enabled
• X-Ray:
  Not Enabled
• Lending: Not Enabled
• Amazon Best Sellers Rank: #175,595 Paid in Kindle Store (See Top 100 Paid in Kindle Store)
  • #14 in Kindle Store > Kindle eBooks > Nonfiction > Professional & Technical > Professional Science > Biological Sciences > Biostatistics
  • #26 in Kindle Store > Kindle eBooks > Nonfiction > Professional & Technical > Medical eBooks > Internal Medicine > Infectious Disease > Epidemiology
  • #31 in Kindle Store > Kindle eBooks > Nonfiction > Professional & Technical > Medical eBooks > Research
• #14 in Kindle Store > Kindle eBooks > Nonfiction > Professional & Technical > Professional Science > Biological Sciences > Biostatistics
• #26 in Kindle Store > Kindle eBooks > Nonfiction > Professional & Technical > Medical eBooks > Internal Medicine > Infectious Disease > Epidemiology
• #31 in Kindle Store > Kindle eBooks > Nonfiction > Professional & Technical > Medical eBooks > Research

Fundamentals of Clinical Trials PDF

I attended Lawrence Friedman's course in clinical trial management at the Münster Epidemiology Summer school in two successive years because it was so good. The book is even better.

By biermam

Used this with my course on clinical research methods. Very exhaustive description of the details of clinical trial design, implementation, analysis and reporting. Recommended for any clinical researcher conducting or wanting to improve their knowledge of clinical trials.

By Deepak Parakkal